Potential use of COX-2–aromatase inhibitor combinations in breast cancer

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

15 صفحه اول

Complementary medicine use among Iranian breast cancer

A cross-sectional study was conducted to evaluate use of complementary medicine by cancer patients, in two comprehensive clinics, in Tehran, Iran. This paper reports the results for breast cancer patients. Design: A specially designed questionnaire was completed for 177 breast cancer patients after informed consent was obtained. The Mean age of the participants was 47.61 years (SD= + 15.1) rang...

متن کامل

Complementary medicine use among Iranian breast cancer

A cross-sectional study was conducted to evaluate use of complementary medicine by cancer patients, in two comprehensive clinics, in Tehran, Iran. This paper reports the results for breast cancer patients. Design: A specially designed questionnaire was completed for 177 breast cancer patients after informed consent was obtained. The Mean age of the participants was 47.61 years (SD= + 15.1) rang...

متن کامل

COX-2 inhibitor nimesulide analogs are aromatase suppressors in breast cancer cells.

Cyclooxygenase-2 (COX-2) inhibitor nimesulide derivatives compounds A and B decreased aromatase activity in breast cancer cells via a novel mechanism different to aromatase inhibitors (AIs), and were defined as "aromatase suppressors". Breast carcinoma cells (MCF-7aro and T47Daro) transfected with aromatase full gene were used to explore the mechanisms of the two compounds. They dose and time-d...

متن کامل

COX-2 inhibitors and breast cancer.

The cyclooxygenase ( COX ) -2 inhibitor celecoxib was recently approved in the USA for the prevention of polyp formation in familial adenomatous polyposis, a defined premalignant condition for colorectal cancer. The potential value of COX inhibitors in similar roles for other malignancies, particularly breast cancer, is therefore currently under intense scrutiny. Use of these medications in che...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: British Journal of Cancer

سال: 2005

ISSN: 0007-0920,1532-1827

DOI: 10.1038/sj.bjc.6602690